Assessment of Minimal Hepatic Encephalopathy (with Emphasis on Computerized Psychometric Tests)

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Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric tests.

AIM To assess whether non invasive blood flow measurement by arterial spin labeling in several brain regions detects minimal hepatic encephalopathy. METHODS Blood flow (BF) was analyzed by arterial spin labeling (ASL) in different brain areas of 14 controls, 24 cirrhotic patients without and 16 cirrhotic patients with minimal hepatic encephalopathy (MHE). Images were collected using a 3 Tesla...

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Minimal Hepatic Encephalopathy (MHE)

1. Episodic (precipitant-induced) encephalopathy, commonly seen in the hospital setting, where a superimposed event is a key factor. 2. Persistent (chronic) encephalopathy, seen with extensive portal–systemic shunts and after portocaval shunt surgery or placement of transjugular intrahepatic portosystemic shunt (TIPS). 3. Minimal (subclinical) encephalopathy reflects alterations in cognitive fu...

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Minimal hepatic encephalopathy.

Minimal hepatic encephalopathy (MHE) is the mildest form of spectrum of hepatic encephalopathy (HE). Patients with MHE have no recognizable clinical symptoms of HE but have mild cognitive and psychomotor deficits. The prevalence of MHE is high in patients with cirrhosis of liver and varies between 30% and 84%; it is higher in patients with poor liver function. The diagnostic criteria for MHE ha...

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Minimal hepatic encephalopathy

Hepatic encephalopathy (HE) is a neuropsychiatric disorder that may accompany either acute or chronic liver disease. It is defined as a disturbance of central nervous system function due to hepatic insufficiency and includes a large spectrum of clinical manifestations such as decreased intellectual function, personality disorders, alterations in level of consciousness and neuromuscular dysfunct...

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Minimal hepatic encephalopathy.

The term minimal hepatic encephalopathy (MHE) refers to the subtle changes in cognitive function, electrophysiological parameters, cerebral neurochemical/neurotransmitter homeostasis, cerebral blood flow, metabolism, and fluid homeostasis that can be observed in patients with cirrhosis who have no clinical evidence of hepatic encephalopathy; the prevalence is as high as 84% in patients with hep...

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ژورنال

عنوان ژورنال: Clinics in Liver Disease

سال: 2012

ISSN: 1089-3261

DOI: 10.1016/j.cld.2011.12.002